Dr. Leslie Greenberg's Blog

The prevalence of oral human papillomavirus is nearly three times higher in men than in women. You may ask “Why does this matter?”… oral HPV infection causes a subset or oropharyngeal squamous cell carcinoma (OSCC).

Litle tidbits.

  • HPV type 16 is the subtype of HPV associated with OSCC.
  • The peak prevalence of oral HPV occurred in people aged 30-34 (7.3%) and 60-64 years (11.4).
  • The risk increased significantly as the number of sex partners for any type of sex increased.
  • Cigarette smoking increases risk of oral HPV infection.
  • The incidence of HPV-positive oropharyngeal cancers increases 225% between 1988 and 2004.

Studies are needed to test HPV vaccines against oral HPV infections.

Source: JAMA 2012; 307

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